The Universal Connector for next-Generation Diagnostics
We standardize how diagnostic tests are built — enabling faster development, true
multiplexing, and seamless integration across platforms.
From lab innovation to real-world impact, ColImBrick turns complex biology into a
modular, scalable interface.
Diagnostics are not limited by biology
but by their interface.
Over the past decades, thousands of biomarkers have been discovered, yet only a fraction are translated into usable diagnostic tests.
The bottleneck lies in how biological components are connected to diagnostic platforms.
Today’s standard approaches rely on rigid surface chemistry, forcing trade-offs between sensitivity, speed, and multiplexing. As a result, innovation slows down,
development costs increase, and most tests remain limited to a single parameter
while diseases are inherently multi-factorial
Statistics
70%
R&D costs devoted to surface optimization and platform redesign
<10%
Of identified biomarkers are successfully transferred to rapid tests
Current standard
(Streptavidin / Biotin) is non-multiplexable and prone to interference
A universal biological interface for diagnostics
ColImBrick introduces a new way to build diagnostic assays.
Instead of directly immobilizing biological reagents onto surfaces, we use engineered protein pairs to create a modular connection layer. This approach transforms complex biochemical interactions into a simple, plug-and-play system enabling consistent performance across platforms.
Build once. Deploy everywhere.
HOW IT WORKS ?
Anchoring
Colicin proteins are immobilized on the diagnostic surface, creating a stable and universal capture layer.
Recognition in solution
Biological reagents bind their targets in solution, preserving their natural conformation and maximizing interaction efficiency.
Assembly
The immune pair locks the complex onto the surface, forming a highly specific and stable detection system.
This decoupling of recognition and immobilization removes the traditional constraints of assay design.
Designed for performance, scalability, and simplicity
ColImBrick combines the strength of high-affinity protein interactions with a modular architecture, unlocking new levels of performance
and flexibility in diagnostic design.
Optimized orientation
Biological reagents are always correctly positioned, maximizing signal capture.
High-affinity binding
Robust, near-covalent interactions ensure stability and reproducibility.
Platform-agnostic
Compatible with LFA, ELISA, beads, microfluidics, and future diagnostic systems.
Reduced development time
Eliminate repeated surface optimization for each new test.
True multiplexing
700+ orthogonal pairs enable simultaneous detection of multiple biomarkers without cross-reactivity.
One technology. Multiple applications.
ColImBrick is designed as a universal layer that integrates seamlessly across diagnostic platforms and use cases — from research to real-world deployment.
Accelerating diagnostic development
We provide a modular technology that empowers diagnostic developers to build faster, more robust, and multiplexed assays — without redesigning their platforms.
Next-generation diagnostic solutions
We also develop proprietary multiplex tests targeting high-impact applications such as clinical monitoring, decentralized testing, and preventive health.
Bridging science and industry
Alejandra Mier
CSO / CO-FOunder
Scientific Architecture of ColImBrick
Panel Development & Analytical Validation
Long-Term Technology Strategy
Christophe Védrine
CSO / CO-FOunder
Strategic Vision & Project Steering
Technology Valorization & Partnerships
Science – Industry – Investors Interface